PT-141

CAS 189691-06-3 · Neuro Research

10 MG

$29.00

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⚠ RESEARCH USE ONLY

This product is sold strictly for in vitro laboratory research use only. Not for human or animal consumption, diagnostic use, or therapeutic application. Purchasers must be qualified researchers or authorized purchasers for a research institution.

CERTIFICATE OF ANALYSIS

Third party tested for: Purity · ID · Quantity

BATCH #20261101 View All →

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PT-141 Overview

PT-141 (bremelanotide) is a synthetic cyclic heptapeptide melanocortin receptor agonist, structurally derived from the alpha-MSH analog Melanotan II. It acts primarily at the MC3 and MC4 receptors in the central nervous system.

In research models, PT-141 has been examined for its role in melanocortin receptor signaling, central pathways involved in sexual arousal and behavior, and energy-balance and cardiovascular endpoints.

Reference: Pfaus J. G. et al. (2004), Proc Natl Acad Sci U S A, 101(27), 10201-10204.

History

PT-141 emerged from research on Melanotan II, a nonselective melanocortin agonist, in which investigators noted effects on sexual behavior unrelated to pigmentation. The compound was developed by Palatin Technologies as a refined analog and has since been studied in a substantial body of preclinical and clinical research on melanocortin pathways.

Reference: Pfaus J. G. et al. (2004), Proc Natl Acad Sci U S A, 101(27), 10201-10204.

PT-141 Structure

CAS #: 189691-06-3

Molecular Formula: C₅₀H₆₈N₁₄O₁₀

Molecular Weight: 1,025.2 g/mol

PubChem CID: 9941379

Research Findings

PT-141 has been studied in cell-based receptor assays, rodent behavioral models and clinical research settings. Reported findings describe central rather than peripheral mechanisms of action.

Key Areas of Research:

MC3/MC4 signaling: Receptor activation and downstream cAMP signaling in vitro
Behavioral models: Sexual-behavior endpoints in rodent research
Central pathways: Hypothalamic circuits associated with arousal
Cardiovascular endpoints: Blood-pressure and heart-rate effects in clinical studies

These observations make PT-141 a widely used research tool for studying melanocortin receptor biology in the central nervous system.

Reference: Kingsberg S. A. et al. (2019), Obstet Gynecol, 134(5), 899-908.

References

Frequently Asked Questions

Everything you need to know about our products and processes.

Each vial contains the exact quantity listed on the label. A 10 mg vial contains 10 mg of lyophilized peptide. Research-grade purity supports accurate dosing for experimental protocols.

Peptides ship as lyophilized powder. Every order includes a complimentary vial of bacteriostatic water for reconstitution. Any additional supplies (syringes, mixing vials, etc.) must be sourced separately by the research institution.

Sealed lyophilized peptide remains stable for approximately 2 years when stored properly. After reconstitution, the solution should be refrigerated and typically retains stability for several weeks depending on temperature and handling conditions.

No. Our products are supplied strictly for in vitro laboratory research. Because these compounds are not authorized for use on humans or animals outside approved research settings, we do not provide usage or dosing instructions.

All peptides are guaranteed to be at least 98% pure, verified by HPLC and mass spectrometry. A Certificate of Analysis is available for every batch.

Keep lyophilized peptides in a cool, dry place away from direct heat and light. Once reconstituted, refrigerate the solution to maintain stability and preserve peptide integrity.