CAS 170851-70-4 · Endocrine Research
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⚠ RESEARCH USE ONLY
This product is sold strictly for in vitro laboratory research use only. Not for human or animal consumption, diagnostic use, or therapeutic application. Purchasers must be qualified researchers or authorized purchasers for a research institution.
CERTIFICATE OF ANALYSIS
Third party tested for: Purity · ID · Quantity
Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) that acts as a selective agonist of the growth hormone secretagogue receptor (GHS-R1a, the ghrelin receptor).
In research models, Ipamorelin has been examined for its role in pulsatile growth hormone release, GH/IGF-1 axis signaling, gastrointestinal motility, and bone and body-composition endpoints.
Reference: Raun K. et al. (1998), Eur J Endocrinol, 139(5), 552-561.
Ipamorelin was characterized in the late 1990s by researchers at Novo Nordisk as the first selective growth hormone secretagogue, distinguished from earlier GHRPs by its lack of notable stimulation of ACTH and cortisol in the models studied. It has since been evaluated in preclinical work and in clinical research, including studies of postoperative gastrointestinal function.
Reference: Raun K. et al. (1998), Eur J Endocrinol, 139(5), 552-561.
CAS #: 170851-70-4
Molecular Formula: C38H49N9O5
Molecular Weight: 711.9 g/mol
PubChem CID: 9831659
Ipamorelin has been studied in cell-based assays, rodent and swine models, and early-phase human research settings. Reported findings describe dose-dependent GH release with a comparatively selective endocrine profile.
Key Areas of Research:
These observations make Ipamorelin a widely used research tool for studying ghrelin-receptor biology and the GH/IGF-1 axis.
Reference: Beck D. E. et al. (2014), Int J Colorectal Dis, 29(12), 1527-1534.
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