Tesamorelin

CAS 218949-48-5 · Endocrine Research

10 MG

$69.00

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⚠ RESEARCH USE ONLY

This product is sold strictly for in vitro laboratory research use only. Not for human or animal consumption, diagnostic use, or therapeutic application. Purchasers must be qualified researchers or authorized purchasers for a research institution.

CERTIFICATE OF ANALYSIS

Third party tested for: Purity · ID · Quantity

BATCH #202610071612 View All →

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Tesamorelin Overview

Tesamorelin is a synthetic 44-amino-acid analog of human growth hormone-releasing hormone (GHRH 1-44), modified with a trans-3-hexenoyl group at the N-terminus to increase resistance to enzymatic degradation.

In research models, Tesamorelin has been examined for its role in stimulating pituitary growth hormone release, GH/IGF-1 axis signaling, visceral adipose tissue biology, and hepatic fat metabolism.

Reference: Falutz J. et al. (2007), N Engl J Med, 357(23), 2359-2370.

History

Tesamorelin was developed in the 1990s and 2000s as a stabilized GHRH analog. The N-terminal trans-3-hexenoyl modification protects the peptide from dipeptidyl peptidase-IV cleavage, extending its activity relative to native GHRH. It has since been the subject of extensive preclinical and clinical research in the GH-axis literature.

Reference: Falutz J. et al. (2010), J Clin Endocrinol Metab, 95(9), 4291-4304.

Tesamorelin Structure

CAS #: 218949-48-5

Molecular Formula: C₂₂₁H₃₆₆N₇₂O₆₇S

Molecular Weight: 5,136 g/mol

PubChem CID: 16137828

Research Findings

Tesamorelin has been studied in cell-based assays, animal models and human research settings. Reported findings describe increased pulsatile GH secretion and downstream IGF-1 changes, along with effects on body-composition endpoints.

Key Areas of Research:

GH secretion: Stimulation of pulsatile pituitary growth hormone release
IGF-1 axis: Downstream changes in circulating IGF-1 in research studies
Visceral adiposity: Visceral adipose tissue endpoints in clinical research
Hepatic fat: Liver-fat endpoints in published human studies

These converging observations make Tesamorelin a widely used research tool for studying GHRH receptor signaling and the GH/IGF-1 axis.

References: Falutz J. et al. (2007), N Engl J Med, 357(23), 2359-2370.; Falutz J. et al. (2010), J Acquir Immune Defic Syndr, 53(3), 311-322.

References

Frequently Asked Questions

Everything you need to know about our products and processes.

Each vial contains the exact quantity listed on the label. A 10 mg vial contains 10 mg of lyophilized peptide. Research-grade purity supports accurate dosing for experimental protocols.

Peptides ship as lyophilized powder. Every order includes a complimentary vial of bacteriostatic water for reconstitution. Any additional supplies (syringes, mixing vials, etc.) must be sourced separately by the research institution.

Sealed lyophilized peptide remains stable for approximately 2 years when stored properly. After reconstitution, the solution should be refrigerated and typically retains stability for several weeks depending on temperature and handling conditions.

No. Our products are supplied strictly for in vitro laboratory research. Because these compounds are not authorized for use on humans or animals outside approved research settings, we do not provide usage or dosing instructions.

All peptides are guaranteed to be at least 98% pure, verified by HPLC and mass spectrometry. A Certificate of Analysis is available for every batch.

Keep lyophilized peptides in a cool, dry place away from direct heat and light. Once reconstituted, refrigerate the solution to maintain stability and preserve peptide integrity.